End-Stage Renal Disease in Patients with Fabry Disease

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End-stage renal disease in patients with Fabry disease.

Anderson-Fabry disease (AFD) is a rare cause of end-stage renal disease (ESRD). Renal pathology in AFD is notable for diffuse deposition of glycosphingolipid in the renal glomeruli, tubules, and vasculature. Light microscopic findings include a “foamy” appearance of the glomeruli with diffuse swelling and vacuolization of visceral podocytes. Electron microscopic findings show podocytes and mesa...

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ژورنال

عنوان ژورنال: Journal of the American Society of Nephrology

سال: 2002

ISSN: 1046-6673,1533-3450

DOI: 10.1097/01.asn.0000015237.87719.dc